Can the mystical experiences of saints/mystics be duplicated by chemical means?

hmmm.. I have heard spiritual people taking certain drugs for the purpose ie of aiding the progress maybe and (its totally true that some of them do use drugs --those who decide to be more un orthodox and experimenting )besides i have read from many sources (and think it could be true too)that drugs and psychedelic effects can awaken the kundalini and that is not safe and can be a dangerous way as purity is a requisite to awaken Goddess